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Lemmon 714 is a sedative and hypnotic medication. It was sold under the brand names Quaalude and Sopor among others and sold as a combination drug under the brand name Mandrax which contained 300 mg methaqualone and 25mg diphenhydramine within the same tablet. Commercial production of methaqualone was halted due to widespread abuse and addictiveness. It is a member of the quinazolinone class.
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Methaqualone, sold under the brand name Quaalude in the US and Mandrax in the UK and South Africa, is a sedative and hypnotic medication. It is a member of the Quinazolinone class.
Researchers in the 1950s first noted the sedative-hypnotic activity of methaqualone. In 1962, methaqualone was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant.
Medical use of Quaaludes
Methaqualone is a sedative that increases the activity of the GABA receptors in the brain and nervous system, similar to benzodiazepines and barbiturates. When GABA activity is increased, blood pressure drops, and breathing and pulse rates slow, leading to a state of deep relaxation. These properties explain why methaqualone was originally mainly prescribed for insomnia.
Methaqualone became increasingly popular as a recreational drug and club drug in the late 1960s and 1970s, known variously as “ludes” or “sopers” (also “soaps”) in the U.S. and “mandrakes” and “mandies” in the UK, Australia, and New Zealand. The drug was often used by hippies and people who danced at glam rock clubs in the 1970s and at discos. The drug was so popular in the disco scene of the 1970s that the drug, sold under the brand name Quaaludes, was nicknamed disco biscuits. Buy Quaaludes online.
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In prescribed doses, Quaaludes promote relaxation, sleepiness, and sometimes a feeling of euphoria. It causes a drop in blood pressure and slows the pulse rate. These properties are the reason why it was initially thought to be a useful sedative and anxiolytic.
In 1972, Quaaludes were one of the most prescribed sedatives in United States.
It became a recreational drug due to its euphoric effect. Quaaludes were a popular drug of abuse during much of the 1970s, even though both the United States and Britain tightened control around their use and dispensing. “Luding out” where Quaaludes were taken with wine, became a popular college pastime.
When it was a legal medicine, methaqualone was available in tablet and capsule form and came in different strengths.
Oral Quaaludes dosages were 75-150mg for light sedation. A commonly prescribed dose was 300mg. Up to 600mg was used for strong sedation. Tolerance develops rapidly and some users may take up to 2000mg daily to achieve the same effects.
The onset of action is approximately 30 minutes after taking Quaaludes and the duration of action is between 5 to 8 hours.
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